Advances in Bioscience and Bioengineering

Volume 3, Issue 1, February 2015

  • Using Mortierella alpina as a Novel Platform for Lipid Synthesis Inhibitor Screening

    Md. Shofiul Azam, Zhennan Gu, Haiqin Chen, Yong Q. Chen

    Issue: Volume 3, Issue 1, February 2015
    Pages: 1-10
    Received: 7 April 2015
    Accepted: 11 April 2015
    Published: 23 April 2015
    Abstract: The screening method for discovering new lipid synthesis inhibitors has not been well developed. Lipid synthesis genes are responsible for the synthesis of fatty acids in normal and tumor cells. Mortierella alpina(M. alpina) fungus has been found to produce large amounts of fatty acids because it possesses a full complement of lipid synthesis genes... Show More